Keywords

• N-nitroso-N-methyltyramine
• 84605-04-9
• C9H12N2O2

Quick Details

• ProName: N-nitroso-N-methyltyramine;84605-04-9
• CasNo: 84605-04-9
• Molecular Formula: C9H12 N2 O2
• Appearance: White to off white powder
• Application: experiment research
• DeliveryTime: prompt delivery
• PackAge: Food bags, aluminum foil bags
• Port: Shenzhen/hongkong
• ProductionCapacity: 5000 Gram/Year
• Purity: 99%+ HPLC
• Storage: cool and dry
• Transportation: DHL,EMS,TNT,UPS,EMS,by air,by sea;
• LimitNum: 10 Milligram
• Moisture Content: 0.1%
• Impurity: 0.1%

Superiority

We supply over 20000 types of spot impurity reference materials, with sufficient supply and same day delivery to meet customers' urgent needs for replenishment at any time. The company has its own research and development center and laboratory, and the team members have over ten years of experience in developing drug impurity reference standards. Our website www.molcoo.com covers over 98% of cutting-edge generic drug projects, with complete structural formulas that greatly save customers time in impurity structure analysis and inference. All products undergo strict quality control testing and provide relevant information such as COA, H-NMR, C-NMR, MS/GC-MS, HPLC/GC purity, QNMR quantification, TGA thermogravimetric analysis, IR infrared, UV ultraviolet, two-dimensional (COSY, NOESY, HMBC, HMQC), etc. These structural confirmation spectra ensure quality and reliability. Our products have a wide range of categories, fast delivery time, good quality, and low prices, which can quickly solve various customer needs such as replenishment and consistency evaluation.

Details

WhatsAPP: +86 17320513646                      E-mail: anna@molcoo.com

Product Information (N031287)

• Product Code：N031287
• English Name：N-(4-Hydroxyphenethyl)-N-methylnitrous Amide
• English Alias：N-(4-hydroxyphenethyl)-N-methylnitrous amide
• CAS No.：84605-04-9
• Molecular Formula：CHNO
• Molecular Weight：180.20

Advantages

• High-Purity Reference Standard：Confirmed by HPLC (≥99.0%), NMR, and HRMS, suitable for qualitative/quantitative analysis of nitrosamine impurities.
• Controllable Stability：Stable for 24 months at -20℃ under light-protected, sealed storage; degradation rate <0.3% in methanol solution within 1 month.

Applications

• Drug Safety Testing：Used for LC-MS/MS detection of N-nitroso impurities in related drugs, complying with ICH M7 guidelines for genotoxic impurities.
• Process Optimization：Monitors nitrosation side reactions during drug synthesis to reduce impurity formation via condition adjustment.

Background Description

This compound belongs to nitrosamines, potentially formed by reactions between amines and nitrosating agents during drug synthesis or storage. Nitrosamines pose genotoxic risks, and regulatory agencies (FDA, EMA) enforce strict limits, making research on such impurities crucial for drug quality control.

Research Status

Current research focuses on developing detection methods (e.g., UPLC-MS/MS) and analyzing formation mechanisms of nitrosamine impurities. Studies show that process optimization or inhibitor addition can reduce their content, with toxicology indicating potential mutagenicity requiring limits below 0.1 ppm.

WhatsAPP: +86 17320513646
E-mail: anna@molcoo.com

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The Molcoo Laboratory added drug impurity reference standards, including Baricitinib, Piperazine, Benzylpenicillin, Tranilast and multiple N-Nitroso drug impurities! Now available for immediate delivery!