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Country: China (Mainland)
Business Type:Lab/Research institutions
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Tel: +86-173-20513646
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Province/state: Hu Bei
City: Wuhan
Street: Company address: Room 005, 15th Floor, Building D2, Phase III, Software New Town, No. 8 Huacheng Avenue, East Lake High-tech Development Zone, Wuhan, Hubei Province, China
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CAS NO.92432-50-3
1(10.0-10000)Milligram
Advantages: N-Nitroso Trimetazidine achieves high purity and excellent stability through optimized synthesis processes and strict multi-level purification procedures. Using various precise analytical methods such as nuclear magnetic resonance (NMR), high-resolution mass spectrometry (HRMS), and high-performance liquid chromatography (HPLC), comprehensive structural confirmation and accurate content determination are carried out on the product, ensuring an accurate chemical structure and uniform, stable composition. It can provide a reliable and precise reference substance for drug research, development, and quality control, effectively reducing experimental errors and enhancing the accuracy and reliability of data.
N-Nitroso Trimetazidine
Product Number: T029011
English Name: N-Nitroso Trimetazidine
English Alias: 1-nitroso-4-(2,3,4-trimethoxybenzyl)piperazine
CAS Number: 92432-50-3
Molecular Formula: C14H21N3O4
Molecular Weight: 295.15
Advantages: N-Nitroso Trimetazidine achieves high purity and excellent stability through optimized synthesis processes and strict multi-level purification procedures. Using various precise analytical methods such as nuclear magnetic resonance (NMR), high-resolution mass spectrometry (HRMS), and high-performance liquid chromatography (HPLC), comprehensive structural confirmation and accurate content determination are carried out on the product, ensuring an accurate chemical structure and uniform, stable composition. It can provide a reliable and precise reference substance for drug research, development, and quality control, effectively reducing experimental errors and enhancing the accuracy and reliability of data.
Applications: It is mainly applied to the fields of impurity research, quality analysis, and control of Trimetazidine drugs. During the drug research and development process, it can be used to accurately determine the content of this impurity in drugs and evaluate its potential impact on drug safety and effectiveness. In the quality control of pharmaceutical production, as a key reference substance, it can accurately detect the presence of impurities in products, helping enterprises strictly control drug quality and ensure compliance with relevant domestic and international regulations and quality standards. In addition, it also has important application value in drug stability research, the exploration of drug metabolism pathways, and pharmacological and toxicological evaluations.
Background Description: With the continuous improvement of requirements for drug quality and safety in the pharmaceutical industry, the research on drug impurities has become the core of ensuring drug quality. As a commonly used drug for treating cardiovascular diseases, the control of impurities in Trimetazidine is directly related to patient medication safety and treatment effects. N-Nitroso Trimetazidine, as one of the potential impurities in the drug, in-depth research on its properties, sources, and impacts on the drug is a crucial part of improving the quality control system of Trimetazidine drugs, which helps to enhance drug quality and protect patient health.
Research Status: Currently, research on N-Nitroso Trimetazidine is gradually deepening. Researchers are committed to developing more sensitive and efficient detection technologies, such as ultra-high performance liquid chromatography - tandem mass spectrometry (UPLC-MS/MS) technology and high-resolution gas chromatography - mass spectrometry (HRGC-MS) technology, to achieve trace detection and precise quantification of this impurity. Meanwhile, studies on its generation mechanism during drug synthesis, its interaction mechanism with drug active ingredients, as well as its impact on drug stability and efficacy, are also actively being carried out, aiming to provide more comprehensive and scientific theoretical basis and technical support for the research, development, production, and quality control of Trimetazidine drugs.