Hubei Moxin Biotechnology Co., Ltd
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CAS NO.543-15-7
1(10.0-10000)Metric Ton
Our products are mainly drug impurity reference products, drug standards, analytical chemistry, standard substances, organic chemical synthesis, chemical custom synthesis. For impurity localization, quantification, and quality control in drug development processes. Our laboratory area is more than 5000 square meters, we have more than 20 analytical instruments such as HPLC and MS/LC-MS/GC-MS, we also have TGA, IR and other testing instruments. We have the most advanced SFC preparation separation equipment. We can provide a full range of impurity reference/standard products required for drug development. Most of the impurities are synthesized through the process, there are also many items of impurities can not be obtained by synthetic means, need to be obtained through raw materials, intermediates, crude products or side reactions contained in the trace target compounds, Hubei Moke has a professional impurity preparation and separation technology team, equipped with professional SFC preparation and separation equipment. It can carry out efficient and accurate separation of impurities for complex projects, and solve the problem of impurity preparation for customers.
1. We integrate R&D, production and sales. A 5,000-square-meter high-standard bio-intelligent manufacturing base can ensure high quality and fast delivery of products. The professional sales team ensures that you don't need to worry about pre-sales and after-sales.
2. We focus on pharmaceutical standards, pharmaceutical intermediates, pharmaceutical impurity controls, peptide customization, our own laboratory, and undertake customized synthesis projects.
3. We offer products from gram grade to g grade, in addition, some product specifications and packaging can be customized.
4. We have been deeply engaged in the pharmaceutical field for ten years and have rich experience. At present, customers are all over the world, and have been highly recognized and trusted by customers.
5. We can provide a variety of safe ways to transport goods for you to choose.
Heptaminol Hydrochloride
Product Information
Product Code：H012000A
English Name：Heptaminol Hydrochloride
English Alias：6-amino-2-methylheptan-2-ol hydrochloride
CAS No.：543-15-7
Molecular Formula：CHNO·HCl
Molecular Weight：181.70（145.24 + 36.46）
Advantages
High Purity：Confirmed by HPLC (≥99.5%), combined with multiple techniques such as NMR (1H, 13C), HRMS, and elemental analysis, ensuring stable and reliable product quality to meet high-standard experimental and production requirements.
Good Stability：Stable for 36 months at -20℃ under light-protected, sealed storage; degradation rate <0.2% in conventional aqueous solution environment within 6 months, guaranteeing the accuracy of experimental data and the stability of production batches.
Applications
Raw Material for Cardiovascular Drugs：As a key intermediate for synthesizing cardiovascular drugs, it is used to prepare drugs that enhance myocardial contractility, improve cardiac pumping function, and clinically treat heart failure, cardiogenic shock, and other diseases.
Reference Standard in Pharmaceutical Research：In new drug development, it serves as a standard reference substance to detect the content of related impurities in drugs, helping to establish quality control standards and ensuring the safety and effectiveness of drugs.
Intermediate in Organic Synthesis：In the field of organic synthesis, the reactivity of its amino and hydroxyl groups enables it to be used in constructing various complex compound structures, expanding the synthesis routes of new drugs or functional materials.
Background Description
Heptaminol Hydrochloride (6-amino-2-methylheptan-2-ol hydrochloride) belongs to the class of amino alcohol compounds. Due to its unique chemical structure and physiological activity, it holds an important position in the field of cardiovascular treatment. This compound enhances myocardial contractility by increasing the calcium ion concentration in myocardial cells, thereby improving cardiac function. With the increase in the incidence of cardiovascular diseases globally, the demand for drugs related to Heptaminol Hydrochloride continues to grow. The optimization of its synthesis process, quality control, and development of new applications have become research hotspots in the pharmaceutical field.
Research Status
Synthesis Process Optimization：The current mainstream synthesis method employs Grignard reagent reactions combined with reductive amination steps. By optimizing catalysts (such as using novel nanoscale metal catalysts) and reaction conditions (precisely controlling temperature, pressure, and reaction time), the yield can be increased to over 85%, while reducing the occurrence of side reactions.
Quality Detection Technology：Ultra-high-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) technology, combined with a C18 column and gradient elution conditions, can complete separation within 5 minutes, with a detection limit as low as 0.001 ng/mL, enabling precise detection of trace impurities and ensuring that product quality meets international pharmacopoeia standards.
Clinical Application Expansion：In addition to traditional treatment of heart failure, studies have found that it has potential in improving the recovery of cardiac function after acute myocardial infarction. Relevant clinical trials are underway to explore its broader clinical application value and safety.